hydrogels brain cancer.png

75. “Allosteric Antagonist Modulation of TRPV2 by Piperlongumine Impairs Glioblastoma Progression”

ACS Central Science (2021)

João Conde, R.A. Pumroy, C. Baker, T. Rodrigues, A. Guerreiro, B.B. Sousa, M.C. Marques, B.P. de Almeida, S. Lee, E.P. Leites, D. Picard, A. Samanta, S.H. Vaz, F. Sieglitz, M. Langini, M. Remke, R. Roque, T. Weiss, M. Weller, Y. Liu, S. Han, F. Corzana, V.A. Morais, C.C. Faria, T. Carvalho, P. Filippakopoulos, B. Snijder, N.L. Barbosa-Morais, V.Y. Moiseenkova-Bell, G.J.L. Bernardes


74. “CRISPR Systems for COVID-19 Diagnosis”

ACS Sensors (2021) Featured on COVER

H. Rahimi, M. Salehiabar, M. Barsbay, M. Ghaffarlou, T. Kavetskyy, A. Sharafi, S. Davaran, Subhash C. Chauhan, H. Danafar, S. Kaboli, H. Nosrati, M.M. Yallapu, and João Conde*


73. “Ultrahigh penetration and retention of graphene quantum dot mesoporous silica nanohybrids for image guided tumor regression”

ACS Applied Bio Materials (2021) Featured on COVER

R. Prasad*, N.K. Jain, A.S. Yadav, M. Jadhav, N.N.V. Radharani, M. Gorain, G.C. Kundu, João Conde*, R. Srivastava*


72. “Osteogenic Differentiation of Human Mesenchymal Stem Cells by the Single Action of Luminescent Polyurea Oxide Biodendrimers”

ACS Applied Bio Materials (2020)

Rita F. Pires, Joao Conde* and Vasco D.B. Bonifacio*

Figure 3.tif

71. “Revisiting Gene Delivery to the Brain: Silencing and Editing”

(2021 Biomaterials Science Emerging Investigators Issue)

Biomaterials Science (2020) Featured on COVER

João Conniot, Sepehr Talebian, Susana Simões, Lino Ferreira*, João Conde*


70. “Swallowing the doctor”: an interview with João Conde about the future of nanomedicine”

Nature Communications Biology (2020)

João Conde*


69. “Biomimetic cancer cell membrane coated-nanosystems as next-generation cancer therapies”

Expert Opinion on Drug Delivery (2020)

M. Pereira-Silva, A.C. Santos, João Conde, C. Hoskins, A. Concheiro, C. Alvarez-Lorenzo, F. Veiga

Figure Matter JConde (2).jpg

68. “Why Go NANO on COVID-19 pandemic?”

Matter (2020)

Sepehr Talebian and João Conde*

Nanotechnology-based disinfectants and s

67. “Nanotechnology-based disinfectants and sensors for SARS-CoV-2”

Nature Nanotechnology (2020) COVID-19 Special Issue Featured on COVER

S. Talebian, G.G. Wallace, A. Schroeder*, F. Stellacci* and João Conde*


66. “Tetrazine carbon nanotubes for pretargeted in vivo ‘click-to-release’ bioorthogonal imaging” (VIP paper)

Angewandte Chemie International Edition (2020) Featured on COVER

H. Li, João Conde, A. Guerreiro, G.J.L. Bernardes

Localized Nanotheranostics.png

65. “Localized Nanotheranostics: Recent developments in Cancer Nanomedicine”

Materials Today Advances (2020)

R. Prasad, N.K. Jain, João Conde*, R. Srivastava

Platinum-triggered Bioorthogonal Decagin

64. “Platinum-triggered Bond-cleavage of Pentynoyl amide and N-propargyl handles for Drug-Activation”

Journal of the American Chemical Society (2020) Featured on COVER

B.L. Oliveira, B.J. Stenton, Unnikrishnan V.B., C.R. Almeida, João Conde, M. Negrão, F.S.S. Schneider, C. Cordeiro, M.G. Ferreira, G.F. Caramori, J.B Domingos, R. Fior and G.J.L. Bernardes

Figure 1 new2.tif

63. “Stepwise Assembly of Multimode Liposomal Nanotheranostic Agent for Targeted In Vivo Bioimaging and NIR Light Mediated Cancer Therapy”

Nature Communications Biology (2020)

R. Prasad, N.K. Jain, A.S. Yadav, D.S. Chauhan, J. Devrukhkar, M.K. Kumawat, S. Shinde, M. Gorain, A.S. Thakor, G.C. Kundu, João Conde*, R. Srivastava*

Figure 1.tif

62. “Above and beyond Cancer Therapy: translating biomaterials into clinics”

Trends in Cancer (2020)

João Conde*


61. “Prolonged local in vivo delivery of stimuli-responsive nanogels that rapidly release doxorubicin in triple-negative breast cancer cells”

Advanced Healthcare Materials (2020) Featured on COVER

Y. Zhang, P. Dosta, João Conde, N. Oliva, M. Wang and N. Artzi


60. “Allosteric Antagonist Modulation of TRPV2 by Piperlongumine Impairs Glioblastoma Progression”

Cell Sneak Peek (2019)

C. Baker*, T. Rodrigues*, R.A. Pumroy*, João Conde*, D. Picard, M.C. Marques, B.P. de Almeida, A. Samanta, F. Sieglitz, M. Langini, M. Remke, R. Roque, F. Corzana, C.C. Faria, T. Carvalho, N.L. Barbosa-Morais, V.Y. Moiseenkova-Bell, G.J.L. Bernardes

Cisplatin-Triggered Bioorthogonal Decagi

59. “Cisplatin-Triggered Bioorthogonal Decaging of Amide Bonds for Targeted-Drug Activation in vivo”

ChemRxiv. Preprint (2019)

B. Stenton, B. Oliveira, João Conde, M. Negrão, M. Godinho Ferreira, R. Fior, G. Bernardes

Oral pH sensitive Nanoprobes for Helicob

58. “Oral pH sensitive GNS@ab Nanoprobes for targeted therapy of Helicobacter Pylori without disturbance gut microbiome”

Nanomedicine: Nanotechnology, Biology and Medicine (2019)

X. Zhi, Y. Liu, L. Lin, M. Yang, L. Zhang, L. Zhang, Y. Liu, G. Alfranca, L. Ma, Q. Zhang, H. Fu, João Conde, X. Di, J. Ni, J. Song, D. Cui

Scheme 1.png

57. “Gastric parietal cell and Intestinal goblet cell secretion: a novel cell-mediated in vivo nanoparticle clearance pathway enhanced with diarrhea via Chinese Herbs”

Nanoscale Research Letters (2019)

Y. Liu, K. Liu, M. Yang, Y. Han, Q. Zhang, João Conde, Y. Yang, Y. Han, G. Alfranca, Y. Wang, J. Song, Y. Zhang, J. Ni, J.M. de la Fuente, D. Cui

systemic local_edited.png

56. “Biopolymers for anti-tumor implantable drug delivery systems: Recent advances and future outlook”

Advanced Materials (2018)

S. Talebian, S. Wadeb, J. Foroughi, K. L. Vineb, A. Dolatshahi-pirouz, M. Mehrali, João Conde, G. Wallace


55. “Ferritin nanocarrier traverses the blood brain barrier and kills glioma”

ACS Nano (2018)

K. Fan, X. Jia, M. Zhou, João Conde, J. He, J. Tian, X. Yan

Nanoparticle-antagomiR based targeting o

54. “Nanoparticle-antagomiR based targeting of miR-31 to induce osterix and osteocalcin expression in mesenchymal stem cells”

PLOS ONE (2018)

M. McCully, João Conde, P.V. Baptista, M. Mullin, M.J. Dalby, C.C. Berry


53. “Plasmonic gold nanoparticles for detection of fungi and human cutaneous fungal infections”

Analytical and Bioanalytical Chemistry (2017). Featured on COVER

T. Sojinrin, João Conde*, K. Liu, J. Curtin, H.J. Byrne H, D. Cui, F. Tian*

Figure 1.png

52. “Smart NIR linear and nonlinear optical nanomaterials for cancer theranostics: prospects in photomedicine”

Progress in Materials Science (2017)

T.M. Liu*, João Conde*, T. Lipiński, A. Bednarkiewicz and C.C. Huang*


51. “Fullerene: Biomedical Engineers Get to Revisit an Old Friend”

Materials Today (2017)

S. Goodarzi, T. Da Ros, João Conde, F. Sefat and M. Mozafari

Conspectus Accounts Conde.png

50. “Designing Hydrogels for On-Demand Therapy”

Accounts of Chemical Research (2017)

N. Oliva, João Conde, K. Wang and N. Artzi

Local microRNA delivery targets Palladin

49. “Local microRNA delivery targets Palladin and prevents metastatic breast cancer”

Nature Communications (2016)

A. Gilam, João Conde, D. Weissglas-Volkov, N. Oliva, E. Friedman, N. Artzi and N. Shomron

Epigenetics paper JC1_edited.png

48. “Chiral Antioxidant-based Gold Nanoclusters Reprogram DNA Epigenetic Patterns”

Scientific Reports (2016)

Y. Ma, H. Fu, C. Zhang, S. Cheng, J. Gao, Z. Wang, W. Jin*, João Conde* and D. Cui*

Gold Nanostars for efficient In Vitro an

47. “Gold Nanostars for efficient in Vitro and in Vivo Real-Time SERS Detection and Drug Delivery via Plasmonic-Tunable Raman/FTIR Imaging”

Biomaterials (2016)

F. Tian, João Conde*, C. Bao, Y. Chen, J. Curtin and D. Cui

Hydrogel-based Local Triple-Combination

46. “Local triple-combination therapy results in tumour regression and prevents recurrence in a colon cancer model”

Nature Materials (2016). Highlighted in Science Translational Medicine and Science Bulletin

João Conde*, N. Oliva, Y. Zhang and N. Artzi*

Revisiting the classification of NIR abs

45. “Revisiting the classification of NIR-absorbing/emitting nanomaterials for in vivo bioapplications”

Nature Asia Materials (2016)

T.M. Liu*, João Conde*, T. Lipiński, A. Bednarkiewicz and C.C. Huang*

Biomaterials for Metastasis.png

44. “Biomaterials for Metastasis: Bridging the Gap between Basic and Translational Research”

Advanced Healthcare Materials (VIP paper) (2016). Featured on COVER

João Conde, N. Shomron and N. Artzi*

Figure 1.png

43. “Revisiting the ‘one material fits all’ rule for cancer nanotherapy”

Trends in Biotechnology (2016)

João Conde*, N. Oliva and N. Artzi*

Figure 2.png

42. “3D Hydrogel Scaffold Doped With 2D Graphene Materials For Biosensors And Bioelectronics”

Biosensors & Bioelectronics (2016)

H.S. Song, O.S. Kwon, J.H. Kim, João Conde* and N. Artzi*

Gold Nanoprisms Cancer Theranostic.png

41. “Gold Nanoprisms as a hybrid in vivo Cancer Theranostic platform for in situ Photoacoustic Imaging, Angiography and localized Hyperthermia”

Nano Research (2016)

C. Bao, João Conde, F. Pan, C. Li, C. Zhang, F. Tian, S. Liang, J.M. de la Fuente and D. Cui

Figure 1.png

40. “Dual-Color Emissive Upconversion Nanocapsules for Differential Cancer Bioimaging in vivo”

ACS Nano (2016)

O.S. Kwon, H.S. Song, João Conde, H. Kim, N. Artzi and J.H. Kim

Self-assembled RNA triple helix hydrogel

39. “Self-assembled RNA-triple-helix hydrogel scaffold for microRNA modulation in the tumour microenvironment”

Nature Materials (2016). Highlighted in Science Translational Medicine

João Conde*, N. Oliva, M. Atilano, H.S. Song and N. Artzi*


38. “EDITORIAL: Cancer Nanotheranostics - What have we learned so far?”

Frontiers in Chemistry (2015)

João Conde*, F. Tian, J.M. de la Fuente and P.V. Baptista

The Golden Age in Cancer Nanobiotechnolo

37. “The Golden Age in Cancer Nanobiotechnology: Quo vadis?”

Frontiers in Bioengineering and Biotechnology (2015)

João Conde*

RNAi nanomaterials targeting immune cell

36. “RNAi nanomaterials targeting immune cells as an anti-tumor therapy: the missing link in cancer treatment?”

Materials Today (2015)

João Conde*, C. Arnold, F. Tian and N. Artzi*


35. “Bioresponsive antisense DNA gold nanobeacons as a hybrid in vivo theranostics platform for the inhibition of cancer cells and metastasis”

Scientific Reports (2015)

C. Bao, João Conde*, J. Curtin, N. Artzi, F. Tian and D. Cui

15 years on siRNA delivery beyond the St

34. “15 years on siRNA delivery: beyond the State-of-the-Art on inorganic nanoparticles for RNAi Therapeutics”

Nano Today (2015)

João Conde*, A. Ambrosone, Y. Hernandez, F. Tian, M. McCully, C.C. Berry, P.V. Baptista, C. Tortiglione and J.M. de la Fuente

Figure Nano Research 2.png

33. “Significance of the balance between intracellular glutathione and polyethylene glycol for successful release of small interfering RNA from gold nanoparticles”

Nano Research (2015)

M. McCully, Y. Hernandez, João Conde, P.V. Baptista, J.M. de la Fuente, A. Hursthouse, D. Stirling and C.C.Berry

Types of AuNPs_YH.jpg

32. “Gold Nanoparticle-siRNA Mediated Oncogene Knockdown at RNA and Protein level, with associated Gene effects”

Nanomedicine (Lond.) (2015)

H.W. Child, Y. Hernandez, João Conde, M. Mullin, P.V. Baptista, J.M. de la Fuente and C.C. Berry


31. “Investigating the role of shape on the biological impact of gold nanoparticles in vitro”

Nanomedicine (Lond.) (2015)

F. Tian, M.J.D. Clift, A. Casey, P. del Pino, B. Pelaz, João Conde, H.J. Byrne, B. Rothen-Rutishauser, G. Estrada, J.M. de la Fuente and T. Stoeger


30. “Dual targeted immunotherapy via in vivo delivery of biohybrid RNAi-peptide nanoparticles to tumour-associated macrophages and cancer cells”

Advanced Functional Materials (2015). Featured on COVER

João Conde*, C. Bao, Y. Tan, D. Cui, E.R. Edelman, H.S. Azevedo, H.J. Byrne, N. Artzi and F. Tian*

POXylated dendrimers for drug delivery.p

29. “POxylated polyurea dendrimers: Smart core-shell vectors with IC50 lowering capacity”

Macromolecular Bioscience (2015)

R.B. Restani, João Conde, R.F. Pires, P. Martins, A.R. Fernandes, P.V. Baptista, V.D.B. Bonifácio and A. Aguiar-Ricardo

Figure 1.png

28. “RNAi-based glyconanoparticles trigger apoptotic pathways for in vitro and in vivo enhanced cancer-cell killing”

Nanoscale (2015)

João Conde, F. Tian, Y. Hernandez, C. Bao, P.V. Baptista, D. Cui, T. Stoeger and J.M. de la Fuente


27. “The next generation of smart gold nanobeacons: nanotheranostics is ready for prime-time”

Nanomedicine (Lond.) (2015)

João Conde* & N. Artzi*

Figure 2.png

26. “Personalizing biomaterials for precision nanomedicine in light of local tissue microenvironment”

Advanced Healthcare Materials (2015). Featured on COVER

N. Oliva, S. Unterman, Y. Zhang, João Conde, H.S. Song and N. Artzi


25. “Implantable hydrogel embedded dark-gold nanoswitch as a theranostics probe to sense and overcome cancer multidrug resistance”

PNAS (2015). Highlighted in Nature Reviews Drug Discovery

João Conde*, N. Oliva and N. Artzi*

Are RNAi and miRNA therapeutics truly de

24. “Are RNAi and miRNA therapeutics truly dead?”

Trends in Biotechnology (2015)

João Conde* & N. Artzi*


23. “Target-Responsive DNA/RNA nanomaterials for microRNA sensing and inhibition: the jack-of-all-trades in cancer nanotheranostics?”

Advanced Drug Delivery Reviews (2015)

João Conde*, E.R. Edelman and N. Artzi


22. “Polyurea dendrimer for efficient cytosolic siRNA delivery”

RSC Advances (2014)

R.B. Restani, João Conde, P.V. Baptista, M.T. Cidade, A.M. Bragança, J. Morgado, I.J. Correia, A. Aguiar-Ricardo and V.D.B. Bonifácio

Figure 1 new.png

21. “A promising road with challenges: where gold nanoparticles are in translational research?”

Nanomedicine (Lond.) (2014)

C. Bao, João Conde, E. Polo, P. del Pino, M. Moros, P.V. Baptista, V. Grazu, D. Cui and J.M. de la Fuente

Figure 3.png

20. “Revisiting 30 years of Biofunctionalization and Surface Chemistry of Inorganic Nanoparticles for Nanomedicine”

Frontiers in Chemistry (2014)

João Conde*, J.T. Dias, V. Grazú*, M. Moros, P.V. Baptista and J.M. De la Fuente

Graphical abstract new.png

19. “Antibody-Drug Gold Nanoantennas with Raman spectroscopic fingerprints for in vivo tumour Theranostics”

Journal of Controlled Release (2014)

João Conde*, C. Bao, D. Cui, P.V. Baptista and F. Tian*


18. “A Gold-nanobeacon system for Gene therapy: evaluation of Genotoxicity, Cell toxicity and Proteome profiling analysis”

Nanotoxicology (2014)

João Conde, M. Larguinho, A. Cordeiro, L.R. Raposo, P.M. Costa,S. Santos, M.S. Diniz, A.R. Fernandes and P.V. Baptista


17. “Gold-Nanobeacons as a theranostic system for the detection and inhibition of specific genes”

Nature Protocol Exchange (2013)

João Conde, J. Rosa and P.V. Baptista


16. “Nanomaterials for reversion of multidrug resistance in cancer: a new hope for an old idea?”

Frontiers in Pharmacology (2013)

João Conde*, J.M. de la Fuente and P.V. Baptista


15. “In vivo tumour targeting via nanoparticle-mediated therapeutic siRNA coupled to inflammatory response in lung cancer mouse models”

Biomaterials (2013)

João Conde, F. Tian, Y. Hernández, C. Bao, D. Cui, K.P. Janssen, M.R. Ibarra, P.V. Baptista, T. Stoëger and J.M. de la Fuente


14. “Gold-Nanobeacons for simultaneous gene specific silencing and intracellular tracking of the silencing events”

Biomaterials (2013)

João Conde, J. Rosa, J.M. de la Fuente and P.V. Baptista


13. “Design of Multifunctional Gold Nanoparticles for in vitro and in vivo Gene Silencing”

ACS Nano (2012)

João Conde, A. Ambrosone, V. Sanz, Y. Hernández, V. Marchesano, F. Tian, H. Child, C.C. Berry, M.R. Ibarra, P.V. Baptista, C. Tortiglione and J.M. de la Fuente


12. “Effect of PEG biofunctional spacers and TAT peptide on dsRNA loading on Gold Nanoparticles”

Journal of Nanoparticle Research (2012)

V. Sanz, João Conde, Y. Hernández, P.V. Baptista, M.R. Ibarra and J.M. de la Fuente


11. “Modification of Plasmid DNA Topology by Histone-Mimetic Gold Nanoparticles”

Nanomedicine (Lond.) (2012)

João Conde, P.V. Baptista, Y. Hernández, V. Sanz and J.M. de la Fuente


10. “Gold-Nanobeacons for Real-Time Monitoring of RNA Synthesis”

Biosensors & Bioelectronics (2012)

J. Rosa & João Conde, J.M. de la Fuente, J.C. Lima and P.V. Baptista

Sem Título.png

9. “Genotoxic effects of occupational exposure to lead and influence of polymorphisms in genes involved in lead toxicokinetics and in DNA repair”

Environment International (2012)

J. García-Lestón, J. Roma-Torres, M. Vilares, R.Pinto, J. Prista, J.P. Teixeira, O. Mayan, João Conde, M. Pingarilho, J.F. Gaspar, E. Pásaro, J. Méndez and B. Laffon


8. “Noble Metal Nanoparticles for Biosensing Applications”

Sensors (Basel) (2012)

G. Doria, João Conde, B. Veigas, L. Giestas, C. Almeida, M. Assunção, J. Rosa and P.V. Baptista


7. “Noble Metal Nanoparticles Applications in Cancer”

Journal of Drug Delivery (2012)

João Conde, G. Doria and P.V. Baptista


6. “Nanophotonics for Molecular Diagnostics and Therapy Applications”

International Journal Photoenergy (2012)

João Conde, J. Rosa, J.C. Lima and P.V. Baptista


5. “Alloy Metal Nanoparticles for Multicolour Cancer Diagnostics”

Proceedings of SPIE (2011)

P.V. Baptista, G. Doria and João Conde


4. “In vitro Transcription and Translation Inhibition via DNA functionalized Gold Nanoparticles”

Nanotechnology (2010)

João Conde, J.M. de la Fuente and P.V. Baptista


3. “Use of Cyclodextrins as Scavengers of Inhibitory Photo-products in Light controlled in vitro Synthesis of RNA”

Journal of Photochemistry and Photobiology A: Chemistry (2010)

A. Vidal Pinheiro, João Conde, A.J. Parola, J.C. Lima and P.V. Baptista


2. “RNA Quantification using Gold Nanoprobes - application to Cancer Diagnostics”

Journal of Nanobiotechnology (2010)

João Conde, J.M. de la Fuente and P.V. Baptista

Sem Título.png

1. “Association of common variants in Mismatch Repair Genes and Breast Cancer susceptibility: a Multigene study”

BMC Cancer (2009)

João Conde, S.N. Silva, A.P. Azevedo, V. Teixeira, J.E. Pina, J. Rueff and J.F. Gaspar