PUBLICATIONs
166. “Targeting osteoblast disulfidptosis with COL4A2-enhanced human mesenchymal stem cells restores bone integrity in osteonecrosis of the femoral head”
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W. Jin, J. Chen, Y. Zhou, C. Zhong, João Conde*, Y. Zhang* and H. Peng*
165. “Single-cell profiling reveals Zn-DHM nanozyme-driven macrophage polarization and ROS scavenging in enhancing muscle regeneration for volumetric muscle loss”
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X. Feng, Z. Luo, W. Zhang, R. Wan, Y. Chen, F. Li, Y. He, Z. Lin, J.H. Hui, Y. Li, João Conde, S. Chen*, Z. Zhao*, X. Wang*
164. “Cancer-associated fibroblast-derived GDF15 induces oxidative stress and neutrophil infiltration in head and neck squamous cell carcinoma through the PI3K/AKT/STAT3 axis cascade”
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Z. Zhao, H. Cai, Z. Zhao, Z. Lin, F. Zhao, K. Zhao, Y. Xi, W. Nie, X. Wang, Y. Ding, L. Lin*, João Conde*, Y. Zhou and Y. Ding*
163. “Integrative multiomics analysis reveals alterations in fecal bile acids and gut microbiome associated with nonalcoholic fatty liver disease progression”
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S. Zhu, Y. Zheng, M. Zou, X. Zhu, Z. Qi, João Conde*, L. Li* and Z. Zhao*
162. “Longan-inspired chitosan-pectin core-shell hydrogel beads for oral delivery of biodrugs to enhance osteoporosis therapy”
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V.H.G. Phan, B-P. T. Nguyen, N.Y. Nguyen, C-N. D. Tran, Q-N. D. Nguyen, C.H. Luu, P. Manivasagan, E-S Jang, D.C. Yang, D.U. Yang, Y. Li* João Conde * and T. Thambi*
161. “Global, regional, and national burden of chronic respiratory diseases and the estimation of excess mortality due to the COVID-19 pandemic, 1990-2021”
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João Conde & GBD Collaborators - Global Burden of Disease (GBD) Consortium
160. “Structurally and functionally optimized silk fibroin-alginate-based biomimetic scaffolds reinforced with bioceramics for bone tissue engineering”
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T-M.N. Nguyen, N-H.H. Le, M. Murugesan, G. Janarthanan, P. Manivasagan, E-S. Jang, Y. Li, V.H.G. Phana, S. Vijayavenkataraman*, João Conde* and T. Thambi*
159. “Aging-associated reduction in ER-mitochondrial contacts impairs mitochondrial lipid metabolism and autophagosome formation in the heart”
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W. Hong, X. Zeng, R. Ma, Y. Tian, H. Miu, X. Ran, R. Song, Z. Luo, D. Ju, D. Ma, M. Ashrafizadeh, S.K. Bhutia, João Conde, G. Sethi*, H. Huang* and C. Duan*
158. “Age-sex-specific burden of urological cancers attributable to risk factors in China and its provinces, 1990–2021, and forecasts with scenarios simulation”
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João Conde & GBD Collaborators - Global Burden of Disease (GBD) Consortium
157. “ANXA1 mRNA-loaded bio-liposomes recover acute pancreatitis by suppressing STING pathway via promotion of efferocytosis in macrophages”
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H. Fang, P. You, Y. Wu, F. Liang, C. Chen, Z. Hou, Z. Wang, J. Lin, L. Chen, S. Zhang, X. Chen, F. Lu, João Conde*, H. Huang* and Y. Pan*
156. “Spatiotemporal single-cell RNA sequencing decodes TP63 and RAC2 as key regulators of efferocytosis and immune modulation in esophageal squamous cell carcinoma”
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Y. Xi, Z. Xu, Z. Zhao, Y. Zhou, C. Yin, W. Jin, C. Lin, J. Kuang, B. Yu*, João Conde*, S. Liu* and W. Shen*
155. “Enzyme-responsive vitamin D-based micelles for paclitaxel controlled delivery in pancreatic cancer therapy”
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Diana Peixoto, João M. Ravasco, B. Blanco-Fernández, F. Veiga, A. Concheiro, João Conde*, A.C. Paiva-Santos* and C. Alvarez-Lorenzo*
154. “RBM30 recruits DOT1L to activate STAT1 transcription and drive immune evasion in hepatocellular carcinoma”
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H. Han, F. Wang, C. Duan, C. Liu, Y. Fu, Y. Wang, D. Zhao, Y. Tian, M. Ashrafizadeh, B. Li, João Conde*, Z. You* and Z. Gong*
153. “Global child and adolescent health in 204 countries and territories with special focus on the impacts of COVID-19, 1990–2021, and forecasts with scenarios simulation to 2040”
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João Conde & GBD Collaborators - Global Burden of Disease (GBD) Consortium
152. “PPDPF-mediated regulation of BCAA metabolism enhances mTORC1 activity and drives cholangiocarcinoma progression”
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Z. Li, Y. Guan, J. Gao, L. Zhu, Z. Zeng, X. Liu, Q. Jing, M. Li, Q. Wan, Q. Fan, X. Ren, H. Pei, D. Zhang, Y. Rong, Z. Rong, L. Cui, Y. Zhang, N. Li, P. Chen, João Conde*, F. Hu*, L. Sun*, Y. Nie* and Y. Deng*
151. “Chitosan- and hyaluronic acid-based hydrogels in cancer therapy and wound healing”
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G. Wu, C. Zhong, X. Tian, M. Ashrafizadeh, M. Ghaffarlou, G. Orive, L. Zha*, João Conde* and X. Feng*
150. “Articular microenvironment remodeling with a disease-modifying drug delivery system for osteoarthritis via metabolic reprogramming therapy”
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Y. Ma, W. Fu, Z. Zhang, C. Sun, Y. Shen, Z. Xiao, L. Liu, M. Li, P. Wang, João Conde*, Q. Yang*, B. Wang* and X. Yua*
149. “Changing life expectancy in European countries 1990-2021: causes and risk factors from the Global Burden of Disease Study 2021”
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João Conde & GBD Collaborators - Global Burden of Disease (GBD) Consortium
148. “Towards a comprehensive understanding of the immunotoxicity of metal-organic frameworks”
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147. “Burden of disease scenarios by state in the USA, 2022–2050: a forecasting analysis for the Global Burden of Disease Study 2021”
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João Conde & GBD Collaborators - Global Burden of Disease (GBD) Consortium
146. “Long-term cell-membrane coated ultrabright polymeric nano-dots for targeted cancer cell imaging and hydrophobic drug delivery”
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Rajendra Prasad*, N. Gupta, A.S. Meena, V.G.S.S. Jyothi, A. Chan-dak and João Conde*
145. “Exploring the link between low germline mutational load and low breast cancer incidence: lessons from the Xavante Indians”
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José Rueff*, João Conde* and Guilherme Castro*
144. “Preclinical validation of a therapeutic intranasal delivery for brain cancer using a hydrogel”
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Leonardo D. Di Filippo, J.L. Duarte, Bárbara B. Mendes, Jhenifer Oliveira, Catarina F. Martins, T.C. Ribeiro, F. Haddad, I.D. Figueiredo, R.M. Sábio, B.S. Rosa, M. Chorilli* and João Conde*
143. “The burden of diseases, injuries, and risk factors by state in the USA, 1990–2021: a systematic analysis for the Global Burden of Disease Study 2021”
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João Conde & GBD Collaborators - Global Burden of Disease (GBD) Consortium
142. “Rational design of Metal-Organic Frameworks for pancreatic cancer therapy: from machine learning screening to in vivo efficacy”
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F. Melle, D. Menon, João Conniot, J. Ostolaza-Paraiso, X. Chen, S. Mercado, Jhenifer Oliveira, Bárbara B. Mendes, João Conde* and D. Fairen-Jimenez*
141. “Engineered biomimetic cisplatin-polyphenol nanocomplex for chemo-immunotherapy of glioblastoma by inducing pyroptosis”
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X. Hao, Y. Tang, W. Xu, M. Wang, J. Liu, Y. Li, J. He, Y. Peng, P. Sun, D. Liao, X. Hu, T. Tang, M. Zhou, R. Han, J. Wang, João Conde*, D. Xiang* and J. Wu*
140. “Accelerating discoveries in cancer nanomedicine using AI”
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C. Guan, Bárbara B. Mendes, João Conniot, A.L. Dias, L. Hammad, T. Thambi, R. Langer*, T. Rodrigues*, João Conde* and C. de la Fuente-Nunez*
139. “Targeted delivery of selective BET inhibitors”
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R. Traquete, E. Henderson, C. Tang, S. Picaud, A. Guerreiro, João Conde, T. Rodrigues, J.D. Seixas, P.M.S.D. Cal, T. Carvalho, R. Wilson, F. Corzana, A. Koehler, C. Goding, P. Filippakopoulos* and G.J.L. Bernardes*
138. “Voices of Nanomedicine: blueprint guidelines for collaboration in addressing global unmet medical needs”
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R. Prasad*, A. Ghosh, V. Patel, B. Peng, Bárbara B. Mendes, E.H.A. Win, L.G. Delogu, J.Y. Wong, K.J. Pische, J. Bellare, A. Bar-Shir, A.S. Thakor, W.J. Parak, Z.M. Bhujwalla, Y.S. Zhang, N. Kommineni, V. Rotello, W. Cai, T. Lammers, T.W. Odom, G. Padmanaban, D. Peer, J.F. Lovell, R. Srivastava*, R. Langer and João Conde*
137. “In vivo nanomicelles modulate key intratumoral and metastatic genomic signalling pathways in pancreatic cancer”
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136. “Nanoscale analysis beyond imaging by atomic force microscopy: molecular perspectives on oncology and neurodegeneration”
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C. Marcuello*, K. Lim, G.Nisini, V.S. Pokrovsky, João Conde and F.S. Ruggeri*
135. “Bioengineered metastatic cancer nanovaccine with a TLR7/8 agonist for needle-free intranasal immunization”
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J.M. Jung, M.S. Lee, Y.K. Seo, J.E. Lee, S.Y. Lim, D.H. Kim, S.Y. Lyu, C. Park, B.D. Kim, J.H. Shin, J.H. Lee, P. Liu, J. Jung, João Conde, T. Thambi, J.H. Jeong and D.S. Lee
134. “Burden of diseases and injuries attributable to risk factors in the European Union (EU-28) in 2019: a systematic analysis for the Global Burden of Disease Study 2019”
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João Conde & GBD Collaborators - Global Burden of Disease (GBD) Consortium
133. “The global burden of acute versus chronic care needs: Analysis of the Global Burden of Disease Study 2019”
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João Conde & GBD 2019 Acute and Chronic Care Collaborators - Global Burden of Disease (GBD) Consortium
132. Voices: “Advancing nanomedicine from lab to clinic through personalized approaches and collaborative innovation”
Cell Reports Physical Science (2024) - IF 8.9
João Conde*
131. “Forecasting the impacts of smoking prevalence scenarios on years of life lost and life expectancy from 2022 to 2050 - a systematic analysis for the Global Burden of Disease Study 2021”
The Lancet Public Health (2024) - IF25.4
João Conde & GBD Collaborators - Global Burden of Disease (GBD) Consortium
129. “Triterpenoid saponin-based supramolecular host-guest injectable hydrogels inhibit the growth of melanoma via ROS-mediated apoptosis”
Materials Science and Engineering: R: Reports (2024) - IF31.6
R. Mathiyalagan, M. Murugesan, Z.M. Ramadhania, J. Nahar, P. Manivasagan, E-S. Jang, D.C. Yang,
João Conde* and T. Thambi*
123. “Global burden and strength of evidence for 88 risk factors in 204 countries and 811 subnational locations, 1990–2021: a systematic analysis for the Global Burden of Disease Study 2021”
The Lancet (2024) - Featured on COVER - IF168.9
João Conde & GBD Collaborators - Global Burden of Disease (GBD) Consortium
122. “Global incidence, prevalence, years lived with disability (YLDs), disability-adjusted life-years (DALYs), and healthy life expectancy (HALE) for 371 diseases and injuries in 204 countries and territories and 811 subnational locations, 1990–2021”
The Lancet (2024) - Featured on COVER - IF168.9
João Conde & GBD Collaborators - Global Burden of Disease (GBD) Consortium
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118. “Preclinical assessment of an antibiotic-free cationic surfactant-based hydrogel for sexually and perinatal transmitted infections”
Matter, Cell Press (2024) - IF20.0
R.D.A. Calado, Bárbara B. Mendes, João Conniot, João M.J.M. Ravasco, D. Sobral, C. Ferreira, R. Ferreira, J.C. Rodrigues, D. Santos, S. Duarte, L. Vieira, A.S. Inácio, H. Carrêlo, W.L.C. Vaz, J.P. Gomes, A. Nunes*, João Conde* and O.V. Vieira*
116. “Engineered nanomaterials for glioblastoma nanovaccination”
Nature Reviews Materials (2024) - Featured on COVER - IF76.7
F. Haamedat, Bárbara B. Mendes, João Conniot, L.D. Di Filippo, M. Chorilli, A. Schroeder, João Conde* and F. Sousa*
113. “Global age-sex-specific mortality, life expectancy, and population estimates in 204 countries and territories and 811 subnational locations, 1950–2021, and the impact of the COVID-19 pandemic”
The Lancet (2024) - Featured on COVER - IF168.9
João Conde & GBD Collaborators - Global Burden of Disease (GBD) Consortium
109. “A Fluorinated BODIPY-Based Zirconium Metal-Organic Framework for in vivo Enhanced Photodynamic Therapy”
Journal American Chemical Society (2024) - IF16.4
X. Chen, Bárbara B. Mendes, Y. Zhuang, João Conniot, S.M. Argandona, F. Melle, Diana P. Sousa, D. Perl, A. Chivu, H. K. Patra, W. Shepard, João Conde* and D. Fairen-Jimenez*
104. “Intratumoural Delivery of mRNA Loaded on a Cationic Hyper-Branched Cyclodextrin-Based Polymer Induced an Anti-Tumour Immunological Response in Melanoma”
Cancers (2023) - IF6.6
F. Trotta, M. Mahmoudian, P. Zakeri-Milani, C. Cecone, K.J. Ishii, T. Hayashi, João Conde, A. Matencio and Y.K. Monfared
99. “Bioengineered exosome membrane camouflaged-abiotic nanocarriers: neurodegenerative diseases, tissue engineering and regenerative medicine”
Military Medical Research (2023) - IF34.9
D. Lopes, J. Lopes, M. Pereira-Silva, Diana Peixoto, N. Rabiee, F. Veiga, O. Moradi, Z.H. Guo, X.D. Wang, João Conde, P. Makvandi and A.C. Paiva-Santos
95. “Exosome Membrane-Coated Nanosystems: Exploring Biomedical Applications in Cancer Diagnosis and Therapy”
Matter, Cell Press (2023) - IF20.0
M. Shao, D. Lopes, J. Lopes, S. Yousefias, A. Macário-Soares, Diana Peixoto, I. Ferreira-Faria, F. Veiga, João Conde, Y. Huang, X. Chen, A.C. Paiva-Santos and P. Makvandi
92. “Magnetite and bismuth sulfide Janus heterostructures as radiosensitizers for in vivo enhanced radiotherapy in breast cancer”
Biomaterials Advances (2022) - IF8.4
H. Nosrati, M. Ghaffarlou, M. Salehiabar, N. Mousazadeh,F. Abhari, M. Barsbay, Y.N. Ertas, H. Rashidzadeh, A. Mohammadi, L. Nasehi, H. Rezaeejam, S. Davaran, A. Ramazani*, João Conde* and H.
Danafar*
87. “Global, regional, and national burden of colorectal cancer and its risk factors, 1990–2019: a systematic analysis for the Global Burden of Disease Study 2019”
The Lancet Gastroenterology & Hepatology (2022) - IF45.0
João Conde & GBD 2019 Colorectal Cancer Collaborators - Global Burden of Disease (GBD) Consortium
86. “PrimeView - Nanodelivery of nucleic acids”
Nature Reviews Methods Primers (2022) - IF50.1
Highlighted in the "Nobel Prize in Physiology or Medicine 2023" Collection
Bárbara B. Mendes, João Conniot, A. Avital, D. Yao, X. Jiang, X. Zhou, N. Sharf-Pauker, Y. Xiao, O. Adir, H. Liang*, J. Shi*, A. Schroeder* and João Conde*
86. “Nanodelivery of nucleic acids”
Nature Reviews Methods Primers (2022) - IF50.1
Highlighted in the "Nobel Prize in Physiology or Medicine 2023" Collection
Bárbara B. Mendes, João Conniot, A. Avital, D. Yao, X. Jiang, X. Zhou, N. Sharf-Pauker, Y. Xiao, O. Adir, H. Liang*, J. Shi*, A. Schroeder* and João Conde*
85. “Burden of non-communicable diseases among adolescents aged 10–24 years in the EU, 1990–2019: a systematic analysis of the Global Burden of Diseases Study 2019”
The Lancet Child & Adolescent Health (2022) - Featured on Cover - IF37.7
João Conde & GBD 2019 Collaborators - Global Burden of Disease (GBD) Consortium
83. “The global burden of adolescent and young adult cancer in 2019: a systematic analysis for the Global Burden of Disease Study 2019”
The Lancet Oncology (2021) - Featured on COVER - IF54.4
João Conde & GBD 2019 Adolescent and Young Adult Cancer Collaborators - Global Burden of Disease (GBD) Consortium
82. “Prodrug polymeric nanoconjugates encapsulating gold nanoparticles for enhanced X-Ray radiation therapy in breast cancer”
Advanced Healthcare Materials (2021) - Rising Star Issue - Featured on COVER - IF11.1
H. Nosrati, F. Seidi, A. Hosseinmirzaei, N. Mousazadeh, A. Mohammadi, Mo. Ghaffarlou, H. Danafar, João Conde* and Ali Sharafi*
80. “Cancer Incidence, Mortality, Years of Life Lost, Years Lived With Disability, and Disability-Adjusted Life Years for 29 Cancer Groups From 2010 to 2019: A Systematic Analysis for the Global Burden of Disease Study 2019”
JAMA Oncology (2021) - IF33.0
João Conde & GBD 2019 Cancer Collaborators - Global Burden of Disease (GBD) Consortium
77. “Global, regional, and national progress toward Sustainable Development Goal 3.2 for neonatal and child health: all-cause and cause-specific mortality findings from the Global Burden of Disease Study 2019”
The Lancet (2021) Featured on COVER - IF202.7
João Conde & GBD 2019 Under-5 Mortality Collaborators - Global Burden of Disease (GBD) Consortium
75. “Allosteric Antagonist Modulation of TRPV2 by Piperlongumine Impairs Glioblastoma Progression”
ACS Central Science (2021) Featured on COVER - IF18.7
João Conde, R.A. Pumroy, C. Baker, T. Rodrigues, (...), F. Corzana, V.A. Morais, C.C. Faria, T. Carvalho, P. Filippakopoulos, B. Snijder, N.L. Barbosa-Morais, V.Y. Moiseenkova-Bell, G.J.L. Bernardes
73. “Ultrahigh penetration and retention of graphene quantum dot mesoporous silica nanohybrids for image guided tumor regression”
ACS Applied Bio Materials (2021) Featured on COVER - IF3.3
R. Prasad*, N.K. Jain, A.S. Yadav, M. Jadhav, N.N.V. Radharani, M. Gorain, G.C. Kundu, João Conde*, R. Srivastava*
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64. “Platinum-triggered Bond-cleavage of Pentynoyl amide and N-propargyl handles for Drug-Activation”
Journal American Chemical Society (2020) Featured on COVER - IF16.4
B.L. Oliveira, B.J. Stenton, Unnikrishnan V.B., C.R. Almeida, João Conde, M. Negrão, F.S.S. Schneider, C. Cordeiro, M.G. Ferreira, G.F. Caramori, J.B Domingos, R. Fior and G.J.L. Bernardes
63. “Stepwise Assembly of Multimode Liposomal Nanotheranostic Agent for Targeted In Vivo Bioimaging and NIR Light Mediated Cancer Therapy”
Communications Biology (2020) - IF6.5
R. Prasad, N.K. Jain, A.S. Yadav, D.S. Chauhan, J. Devrukhkar, M.K. Kumawat, S. Shinde, M. Gorain, A.S. Thakor, G.C. Kundu, João Conde*, R. Srivastava*
60. “Allosteric Antagonist Modulation of TRPV2 by Piperlongumine Impairs Glioblastoma Progression”
Cell Sneak Peek (2019) - IF41.6
C. Baker*, T. Rodrigues*, R.A. Pumroy*, João Conde*, D. Picard, M.C. Marques, B.P. de Almeida, A. Samanta, F. Sieglitz, M. Langini, M. Remke, R. Roque, F. Corzana, C.C. Faria, T. Carvalho, N.L. Barbosa-Morais, V.Y. Moiseenkova-Bell, G.J.L. Bernardes
58. “Oral pH sensitive GNS@ab Nanoprobes for targeted therapy of Helicobacter Pylori without disturbance gut microbiome”
Nanomedicine: Nanotechnology, Biology and Medicine (2019) - IF6.5
X. Zhi, Y. Liu, L. Lin, M. Yang, L. Zhang, L. Zhang, Y. Liu, G. Alfranca, L. Ma, Q. Zhang, H. Fu, João Conde, X. Di, J. Ni, J. Song, D. Cui
57. “Gastric parietal cell and Intestinal goblet cell secretion: a novel cell-mediated in vivo nanoparticle clearance pathway enhanced with diarrhea via Chinese Herbs”
Nanoscale Research Letters (2019) - IF5.4
Y. Liu, K. Liu, M. Yang, Y. Han, Q. Zhang, João Conde, Y. Yang, Y. Han, G. Alfranca, Y. Wang, J. Song, Y. Zhang, J. Ni, J.M. de la Fuente, D. Cui
33. “Significance of the balance between intracellular glutathione and polyethylene glycol for successful release of small interfering RNA from gold nanoparticles”
Nano Research (2015) - IF10.3
M. McCully, Y. Hernandez, João Conde, P.V. Baptista, J.M. de la Fuente, A. Hursthouse, D. Stirling and C.C.Berry
30. “Dual targeted immunotherapy via in vivo delivery of biohybrid RNAi-peptide nanoparticles to tumour-associated macrophages and cancer cells”
Advanced Functional Materials (2015). Featured on COVER - IF19.9
João Conde*, C. Bao, Y. Tan, D. Cui, E.R. Edelman, H.S. Azevedo, H.J. Byrne, N. Artzi and F. Tian*
9. “Genotoxic effects of occupational exposure to lead and influence of polymorphisms in genes involved in lead toxicokinetics and in DNA repair”
Environment International (2012) - IF13.3
J. García-Lestón, J. Roma-Torres, M. Vilares, R.Pinto, J. Prista, J.P. Teixeira, O. Mayan, João Conde, M. Pingarilho, J.F. Gaspar, E. Pásaro, J. Méndez and B. Laffon
